sábado, 3 de novembro de 2012

Hurricane Sandy’s Lesser-Known Victims: Lab Rats


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Among the smaller but still important casualties of Hurricane Sandywere thousands of laboratory rodents, genetically altered for use in the study of heart disease, cancer and mental disorders like autismand schizophrenia, that drowned in basement rooms at a New York University research center in Kips Bay.
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The collection of carefully bred rodents was considered one of the largest and most valuable of its kind in the country. The animals lived in colonies in the cellar of the Smilow Research Center, on 1st Avenue near 30th Street.
New York University medical and research staff worked furiously to protect their human patients — and others threatened by the storm — in all three of its facilities in Kips Bay. Though most of the animals at the center were unharmed, the center staff could not rescue the animals in one of the facilities, despite hours of work amid the flooding that started at the institute on Monday night.
“The combined tide and wind resulted in extensive flooding in the building, and unfortunately, my mouse colonies were wiped out,” said Gordon J. Fishell, associate director of the N.Y.U. Neuroscience Institute. “These animals were the culmination of 10 years of work, and it will take time to replace them.”
N.Y.U. officials said that, storm warnings notwithstanding, there was every reason to expect the Smilow building to be protected; the building was designed to withstand surges 20 percent higher than had historically occurred.
Dr. Fishell said that his lab alone lost about 2,500 mice. Other programs at the Smilow center, including research into cancer, cardiovascular disease and epigenetics, lost a combined 7,500 more animals, both mice and rats, according to faculty estimates. The animals were an important resource, but research in all of these areas is broadly based and will continue, university officials said.
“It’s an absolute tragedy any way you look at it,” Dr. Fishell said.
The colonies are bred to carry some of the same genetic glitches thought to contribute to disorders in humans like high blood pressure, cancer or epilepsy. The Fishell lab has been studying the effect of specific genetic mutations on neurons that inhibit runaway electrical activity in the brain. Such neural overheating is associated with seizures, among other mental symptoms. The mouse lines included about 40 genetic variants.
Medical centers typically have veterinarians on hand, as well as other lab staff, to feed and care for research animals. “That facility is top-notch, one of the leading centers in the country, so the loss is just terrible,” said Dr. Yariv Houvras, a cancer researcher at NewYork-Presbyterian/Weill Cornell Medical Center.
The loss is the second major blow to basic research in developmental disorders in just the past several months. In June, a freezer failure at the Harvard Brain Bank in Belmont, Mass., ruined 150 brain specimens, many of them from people with autism who died young.
Lines of genetically altered animals, like brain banks, are painstakingly built up over time. But the mouse colonies can be restored, researchers said; many of the rodents lost in the storm have genetic relatives living elsewhere, and those animals could be used to begin the process.
Already scientists at two research centers, the University of Pennsylvania and Cold Spring Harbor Laboratory on Long Island, have pledged to donate animals to restart some of the Smilow center’s colonies. “That’s the one really positive thing to come out of this,” Dr. Fishell said. “Individuals in the research community, who in most businesses would be considered my competitors, have been eager to help.
”

Veneno de cobra age contra câncer de pele, aponta estudo do Butantan


Cascavel (Foto: Instituto Butantan/Divulgação)Cascavel é uma espécie de cobra venenosa natural
das Américas (Foto: Instituto Butantan/Divulgação)

Toxina consegue aumentar em até 70% sobrevida de casos de melanoma.
Teste foi feito com cobaias e deve ser estendido a humanos em dois anos.


Uma toxina encontrada no veneno da cobra cascavel poderia aumentar a sobrevida de casos de câncer de pele em até 70%, segundo um estudo feito com camundongos pelo Instituto Butantan, em São Paulo.
Segundo a geneticista Irina Kerkis, que coordenou a pesquisa, a grande vantagem da proteína crotamina é que, na dose certa, ela distingue células normais das cancerosas e consegue entrar dentro destas, com um efeito que dura até 24 horas. Isso permitiria que a substância fosse administrada apenas uma vez por dia, reduzindo os efeitos colaterais da quimioterapia.
"A crotamina inibe o crescimento das células alteradas e as mata. Em alguns casos, o câncer praticamente desapareceu", conta a geneticista, que orientou o trabalho do doutorando da Universidade de São Paulo (USP) Alexandre Pereira, na área de biotecnologia.
A toxina retirada dessa espécie de cobra peçonhenta (Crotalus durissus), que tem um chocalho na cauda e é natural do continente americano, vem sendo estudada desde 2004, mas para outras aplicações. Desde 2009, por meio desse estudo, é que os cientistas analisaram seus efeitos contra o câncer.
Crotamina (Foto: Instituto Butantan/Divulgação)
Crotamina dentro de células cancerosas brilha e
detecta doença (Foto: Instituto Butantan/Divulgação)
Primeiro, foram observadas células humanas e animais isoladas, com ação em tumores de mama e pulmão, por exemplo. Na fase seguinte, com 70 camundongos, os autores – que publicaram o estudo no ano passado na revista britânica "Expert Opinion on Investigational Drugs" – viram que a crotamina foi eficiente na contenção de melanoma, um tipo menos comum de câncer de pele, mas extremamente agressivo, pois se espalha rapidamente para outros órgãos.
Segundo Irina, os testes clínicos com seres humanos devem começar em cerca de dois anos, e dentro de cinco é possível ter um novo medicamento contra o melanoma.
"Os fármacos tradicionais usados na quimioterapia têm grande impacto nas células saudáveis, com muitos efeitos colaterais. Já a crotamina é inofensiva para elas. Além disso, é mais facilmente diluída em água, o que facilita a administração injetável", explica.
O estudo deve continuar agora a pesquisar outras formas de aplicação dessa toxina, por meio de uma "bomba" embaixo da pele que solta a substância em pequenas quantidades durante algumas semanas. Assim, o composto não entra na corrente sanguínea, o que minimiza seu impacto no organismo.
Outro benefício, de acordo com Irina, é que a crotamina das cascavéis não tem o efeito emagrecedor visto nos quimioterápicos normais. Nos testes com cobaias, a proteína mostrou que consegue fazer o indivíduo manter o peso.
A geneticista destaca, ainda, que a substância é uma ferramenta biotecnológica poderosa, que pode ajudar também no diagnóstico do câncer. Isso porque, quando entra nas células cancerosas, a crotamina vira um marcador que detecta o crescimento do tumor e casos de metástase.
"Estamos otimistas, mas ainda é uma pesquisa", ressalta a geneticista.
Segundo ela, uma espécie de escorpião também tem veneno com propriedades parecidas às da crotamina, mas ainda não há pesquisas relacionando o composto com tratamento de câncer.

quinta-feira, 1 de novembro de 2012

OMS alerta sobre possível "catástrofe sanitária" de malária


A Organização Mundial da Saúde (OMS) alertou nesta quarta-feira (31) sobre a "catástrofe sanitária" que poderá ser provocada por uma cepa da malária resistente a medicamentos detectada no Sudeste Asiático.
"Se ela extrapolar seus limites e chegar à África, realmente poderá se transformar em uma catástrofe sanitária pública", disse em Sydney o diretor do Programa sobre Malária da OMS, Robert Newman.
A cepa da malária em questão aumentou sua resistência aos tratamentos com artemisinina na região do Grande Mekong, que inclui áreas do Camboja, Tailândia, Mianmar, Laos e Vietnã.
Por enquanto, os remédios utilizados contra a doença na África seguem sendo efetivos, mas se essa cepa alcançar esse continente os medicamentos poderão perder sua eficácia em médio ou até em curto prazo, segundo especialistas presentes na conferência "Malária 2012: salvando vidas na Ásia-Pacífico".
A conferência na cidade australiana, da qual participam dez ministros da Saúde de países da região, autoridades nacionais, cientistas e outros especialistas em medicina tropical, será encerrada na próxima sexta-feira (2) com uma reunião ministerial liderada pelo enviado especial da ONU para Malária, Ray Chambers.
No mundo todo são registrados anualmente mais de 216 milhões de casos de malária, que é transmitida aos humanos mediante a picada de mosquitos infectados, e, deste total, 655 mil são fatais, de acordo com dados da OMS.
Cerca de 30 milhões de casos são contabilizados a cada ano na região Ásia-Pacífico, onde a doença é endêmica em 22 países e causou a morte de 42 mil pessoas em 2010, a maioria delas em Índia, Mianmar, Bangladesh, Indonésia e Papua Nova Guiné.

Rio de Janeiro muda estratégia de vacinação contra Febre Aftosa


Na campanha que começa nesta sexta-feira, dia 1° de Novembro, serão vacinados apenas animais com até dois anos de idade

Há 15 anos sem o registro de Febre Aftosa em seu rebanho bovídeo, o Estado do Rio de Janeiro inicia a segunda etapa anual de vacinação contra a doença com alteração na estratégia visando a imunização dos animais.
De primeiro a 30 de novembro deverão ser vacinados todos os bovinos e bubalinos (búfalos) com até 24 meses de idade. A mudança é válida para já, na campanha de Novembro. Na primeira etapa da vacinação, que ocorre no mês de Maio, o produtor deverá vacinar novamente todos os animais, em qualquer idade.
De acordo com o secretário estadual de Agricultura, Alberto Mofati, a medida autorizada pelo Ministério da Agricultura e que atende à reivindicação dos pecuaristas fluminenses, foi possível graças aos índices de imunização do rebanho superiores a 90%, alcançados há várias campanhas e que mantém a segurança sanitária contra a doença no estado.
- A decisão representa uma redução de despesas de mais de R$ 1,7 milhão para o setor com aquisição de vacina e pagamento de mão de obra. Além disso, facilita o manejo do rebanho, uma vez que, historicamente a grande quantidade de chuvas no mês de novembro costuma interferir no processo de vacinação. A partir de agora, o problema será reduzido, pois somente os
animais mais jovens serão manejados - frisou Mofati.
O Superintende de Defesa Agropecuária da secretaria estadual de Agricultura, Paulo Henrique Moraes, lembrou que apesar de parcial, após a vacinação continua sendo obrigatória a apresentação da Declaração de Vacinação em um dos Núcleos de Defesa Agropecuária ou Postos Municipais no Estado. Neste documento deverão constar todos os bovídeos da propriedade
tanto os imunizados na etapa Novembro quanto os dispensados.
- A estimativa é que sejam vacinados quase 860 mil animais, que se encontram nesta faixa etária, do total de 2,13 milhões de cabeças do rebanho estadual - frisou ele.
*Secretaria estadual de Agricultura e Pecuária*
*Assessoria de Comunicação – (21) 3607-5404*
*Silvia Queiroz: (21) 8596-8160*
*Ana Angelica Gramático: (21) 8596-8161*

A ten-year plan to phase out live animal exports


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Phasing out live exports may be the only way to save Australia’s northern cattle industry. AAP Image/Dave Hunt
Temporary bans on live cattle and sheep export have undermined confidence in the industry, driving property prices down and diminishing banks' willingness to lend for long-term improvement. If the industry wants to avoid death by a thousand cuts, it must act now to phase out live export.
A phasing out of export of livestock for meat over the next ten years or so may be a necessity for a viable industry in the long term. It would require careful preparation and arrangements for compensation for those adversely affected.

Welfare issues

It is widely recognised that sending animals overseas to slaughter is not the only welfare problem. Indeed it is not even the most important welfare issue for livestock; good nutrition and veterinary care have a much greater impact over the animals' lifetime. However, live export is a welfare issue that we can fix, and developing a long-term solution will be much better for producers than the repeated temporary bans invoked by government.
Australia has little or no control over what happens to exported animals. AAP Image/Animals Australia
Most producers care a great deal for their livestock, and many have been deeply disturbed to see how some of the animals that they so attentively nurtured are treated after they’ve left their property.
These welfare problems are not just the multiple stresses that animals are exposed to during the export process, but Australia’s lack of control of the transport and slaughter process after the animals have arrived at their destination port. Regulatory authorities also have little control over practices on the ships: the stockpeople, vets and crew are employed by the industry so there is no independent authority to oversee the process. In other animal-risk situations, such as abattoirs, government inspectors are present: the same should be true on live export boats.

Markets for meat

The long-term prospects for beef and sheep meat exports from Australia are good. Demand, especially for beef, is increasing as developing countries become more affluent and change to a Western style diet. This will continue while wealth in Eurasia and the Americas transitions from traditionally wealthy countries to those until recently considered poor. Opportunities for export from Australia to Asia are considerable because of the limited land available in Asia for livestock production.
Introducing a permanent ban over a long period would allow Australian producers to adapt their systems. Meatworks would have to be set up in the north of Australia. For many producers, live export is the only option because of the lack of northern abattoirs. It is not economic to truck cattle thousands of kilometres to the nearest abattoirs, Brisbane or Perth. Abattoirs existed in the north until the 1990s but were phased out as the live export trade grew.
Demand for beef is increasing in developing nations. Pankaj Kaushal
Small-scale abattoirs handling some of the northern cattle cannot compete with the high prices paid for animals for live export. Several large-scale abattoirs handling most or all of the cattle would be required if live export is phased out; in fact, it is only if live export is phased out that they could be successful financially. The first is being built just south of Darwin and is expected to be finished next July. Each abattoir would employ several hundred people, including providing potential employment to disadvantaged indigenous communities.
New markets would have to be opened up, but some of the demand that has recently been met by sending live animals could be met by carcases. Ships would have to be adapted to take refrigerated cargo, but efficiency would be increased because they would only carry the consumable product. Carcase comprises approximately half of the weight of each animal, and only about one-half of the carcase is muscle tissue that is eaten. Transporting carcases is therefore cheaper than live animals.
In the short term, the prices that producers receive for their animals would probably fall, making it harder to provide the necessary feed and medications that ensure the welfare of livestock. In the long-term, however, strong world market prices for meat should be sufficient to sustain an efficient industry.

A more diverse, stronger and kinder industry

Australian producers could sell more expensive cuts, such as wagyu. avlxyz/Flickr
Exporting carcases rather than live animals would enable producers to grow the type of animal that their land can support. Rather than having to produce steers of less than 350kg for export from northern Australia to Indonesia, those with good quality land can grow their cattle to higher weights profitably at home.
A greater variety of production methods will be possible, to suit the many different markets around the world. There will be a market for animals at different stages of maturity, with different levels of marbling and subcutaneous fat. Carcases from high quality breeds like Angus and Charolais can be supplied to markets that pay a premium.
The market exposure and risk to producers will be reduced by diversifying the countries to which carcases are sent. Exposure and risk are both very apparent in the current situation where one country – Indonesia – dominates the market.
Australia can become a world animal welfare leader in its livestock production systems. Its outdoor environment offers a natural advantage.
People overseas are well aware of our live export issues. Addressing them before any more damage is done to the industry is vitally important.

Zoonoses de Sorocaba, SP, fazcampanha contra a Leishmaniose


 

Ação será no Jardim das Estrelas e deve colher sangue de 1,5 mil animais.
Secretaria da Saúde identificou uma cadela contaminada no bairro.

Do G1 Sorocaba e Jundiaí
A equipe de Zoonoses de Sorocaba (SP) vai promover uma ação conta a Leishmaniose Visceral Canina na cidade. Os agentes passarão por residências do Jardim das Estrelas, zona oeste da cidade, para tentar detectar animais contaminados.
O problema surgiu quando um caso foi identificado no bairro. A Secretaria Municipal de Saúde divulgou, no dia 2 de agosto, a confirmação de uma cadela, com nove anos, domiciliada no bairro.
Segundo a secretaria, é o primeiro e único caso autóctone - quando é adquirido na cidade - de Leishmaniose. A doença foi confirmada por exame feito pela Superintendência de Controle de Endemias (Sucen), da Secretaria de Estado da Saúde, no dia 30 de julho.
A partir disso, agentes da Zoonoses da cidade vão percorrer um raio de 200 metros da casa onde estava o animal. Eles vão coletar amostras de sangues de outros cães da região. Eles também vão orientar os moradores sobre as medidas de controle.
A contaminação é feita por um mosquito, conhecido como "Mosquito Palha". O inseto habita locais com matéria orgânica, como folhas e frutos que caem das árvores.
A ação começou na manhã desta terça-feira (30) e a expectativa dos agentes da Zoonozes é de coletar amostras de sangue de quase 1,5 mil animais do bairro. A doença pode ser transmitida para humanos, levando à morte.
Confira os principais sintomas da doença em homens e animais:
Homens
Febre com longa duração
Falta de apetite
Emagrecimento
Fraqueza
Barriga inchada

Cães
Além dos sintomas dos homens, também há o crescimento exagerado das unhas

Campanha da Zoonoses deve recolher amostras de sangue de 1,5 mil cães (Foto: Reprodução/TV Tem)Campanha da Zoonoses deve recolher amostras de sangue de 1,5 mil cães (Foto: Reprodução/TV Tem)http://g1.globo.com/sao-paulo/sorocaba-jundiai/noticia/2012/10/zoonoses-de-sorocaba-sp-faz-campanha-contra-leishmaniose.html

25 Feeder Calf Mistakes To Avoid


feedlot calves
Geni Wren
Geni Wren, Bovine Veterinarian Magazine | October 23, 2012

This fall when calves will be entering the feedlot, the feedlot team including the veterinarian, nutritionist, manager, pen riders and feeders will have the opportunity to all work together to get these calves off to a good start.
Beef cattle nutritionists Mike Hubbert, PhD, and Jennifer Schutz, PhD from New Mexico State University’s Clayton Livestock Research Center, says it’s important to “feed for health” with these new calves. “I define feeding for health as: the individual animal is consuming the proper nutrients at the proper units/levels for the promotion of healthy, cost efficient growth,” Hubbert explains.
“What is the biggest deterrent to our success in doing that?” Hubbert asks. “The biggest deterrent depends on the cattle buyer, the facilities we work with, the ingredients from the milling/mixing/moisture levels, the weather we have to deal with, the animal health crews, the feeding crews, feedyard management, the veterinarian and the nutritionist. We have to work together as a team to achieve our goal. Many times that is not done as well as it needs to be done.”
Hubbert says what’s needed is the creation of a “happy zone” that revolves around comfort for the animal, the veterinarian and the nutritionist, based on good animal husbandry. “The better we make this comfort zone and animal husbandry between us, the greater chance for success,” he says. “We can’t have the animal health side working against us and we can’t have the nutritionist working against us. We have to work together.”
25 mistakes
Hubbert and Schutz outline 25 common mistakes and problems that they see as nutritionists that are made with newly arrived calves at feedlots.

Feeding management:
1. Inconsistent feeding times. Cattle should be fed within 15 minutes of when they were fed the prior day, and be fed within 0.2 lb from what was called.
2. Bunks too high for calves. Hubbert says bunks are higher in today’s feedlots because larger calves have been the norm. However, with today’s prices, a lot of smaller calves are coming into the feedyards and they can’t reach into the bunks very well.
3. Cattle standing around. Hubbert says standing costs 15% more in maintenance than lying down. If cattle are standing around waiting on late feed trucks, they are losing energy.
4. Not recording pulls for the feeder. Often pen riders will wait until the feed truck goes by to identify calves that don’t go to the bunk. The mistake is made when after pulling those cattle the feeder is not informed, so at the next feeding the pen will be overfed.
Nutrition:
5. Ration changes to multiple rations. If a feedyard has, for example, four rations that are fed twice a day, making ration changes to these multiple rations becomes very complicated and difficult to be done effectively.
6. Changing type and amount of ration concurrently. Moving up the amount of ration and changing ration at the same time can mess with intakes. Hubbert says you should transition from ration 1 to 2 but keep it at the same level of intake during transition to avoid decreased intakes
7. Not watching moisture levels in diets. Hubbert says moisture levels in different ingredients such as high-moisture corn and wet distiller’s grains can widely vary and that can change energy density. Silage moisture levels can change roughage content. Also watch things like pre-ground hay that is ground so much all the fiber is gone — it becomes not a roughage but a bloat-promoting, highly soluble material.
8. Feeding calves unfamiliar diets. For example, feeding silage to calves that have never seen silage before can reduce or delay intakes. Remember, we are feeding the cattle not the cement feedbunk, watch cattle behavior!
9. Blaming acidosis on everything. Hubbert says it’s common to blame acidosis for dead cattle based on the pH of the rumen after death, which is around 4.8, however, he says, that pH is most often caused by fermentation which continues after death, not acidosis, so be careful in your diagnosis.
10. Not balancing distiller’s grains correctly. Distiller’s grains need to be balanced with the right kind of fiber, Hubbert says. For example, if you combine it with alfalfa, you’ll most likely create diarrhea. Also, make sure fiber sources are not cut in too large of pieces or cattle will sort the feed.
11. Not paying attention to ingredient processing. For example, Hubbert says, ground wheat digests very rapidly and can cause metabolic upsets as acidosis, so using cracked corn or a “heavy” steam-flaked wheat or corn is probably the most easily digestible diet. Steam-flaking corn to an industry average 28 lb/bu flake, will increase the starch availability of the corn kernel which will improve performance without excessively high rates of fermentation. Hubbert says corn by-products such as corn gluten feed or Sweet Bran (Cargill) are great to substitute for grain in starting diets as they are high energy without the rapidly digestible starch component.
12. Feeding the wrong forages to new calves. Hubbert notes that alfalfa in starting diets can increase lipopolysaccharides and endotoxins, and Sudan hay can have nitrates. Grass hay is great, he says, and hulls have great palatability. Silage can be used depending on the cattle and if they are familiar with it.
13. Feeding ingredients free-choice. When possible, Hubbert recommends that ingredients are mixed instead of free-choice to avoid sorting.
14. Not considering amino acid profiles. Amino acid profiles, especially on corn by-products, can be altered during fermentation. Hubbert recommends using less than 1% of urea in incoming diets because urea adaptation by rumen microorganisms takes around 12–14 days.
15. Not analyzing fat source. Hubbert says the nutritional value of fat sources vary quite a bit. Vegetable fat can be consistent and have a high free fatty acid; and yellow grease is the most variable in free fatty acids, which can kill cattle if not managed properly.
16. Not supplying minerals. Calcium and phosphorous are important in receiving diets. Hubbert assumes a trace mineral deficiency and includes them at 150%. He also sticks with Vitamin E 
levels at about 400 IUs.

Stress:
17. Receiving pens in high-stress location. Having receiving pens next to shipping pens, the mill, etc. can cause newly arrived cattle to get no rest, and increases stress which can decrease intake.
18. Mixing wild cattle with bunk-broke cattle. Wild cattle that are not used to feed bunks won’t mix with other cattle and get to the bunk and eat. Hubbert says they should be sorted off or handled differently, including shortening the pen, placing extra feed troughs in the pen, feeding at night to lower aggravation, etc.
19. Not resting new calves. Hubbert says incoming calves need some rest after transit, and that many feedlots don’t take into consideration the total transit time the calves have gone through, not just the last transit to the feedlot.
20. Castrated calves with non-castrated calves. Putting newly castrated calves with non-castrated calves can cause problems, as for the first few days the newly castrated calves don’t want to get bumped around, and will be more hesitant to crowd up to the bunk. Hubbert says if there are enough of them, separate them.
21. Small and large calves together. Putting 400-lb calves and 700-lb calves in pens together can result in the larger calves dominating the bunk. Hubbert says the smaller calves won’t eat for a few days, then they will make a break for it and gorge themselves.
Hospitals:
22. Insufficient water trough space in the hospital. Hubbert says work in 1999 showed that sick cattle like to hang out by waterers, “but we still don’t give them more than the 2–4 inches as we do in the home pen,” he says. Competition with other hospital pen cattle can reduce water intake.
23. Overfeeding/underfeeding hospital cattle. It’s important to have a fairly accurate headcount of hospital pen cattle so that the correct amount of feed can be fed to avoid creating acidosis in those most sensitive to it.
24. Not cleaning the hospital pen and bunk. Regular pens get slick bunks multiple times a day, but hospital pen bunks may only get cleaned out once a week. Unappetizing rations that sit around in the hospital bunk can also be at risk for molds, especially with high-moisture feeds.
25. No salt or mineral blocks in the hospital pens. Sick calves need vitamins and minerals to help with immune function and health.

Vaccinating Pregnant Cows: Reproduction


South Dakota State University Extension | October 22, 2012
When a cow is in the chute for pregnancy checking, many cow-calf producers take advantage of the opportunity to perform other necessary procedures to get their cows ready for the winter and the subsequent calving season. For some producers, vaccinating cows is on this list of tasks. But should it be? 
There are two main disease categories for which most producers vaccinate cows. One of them is to boost colostrum quality by vaccinating against calf scours organisms. The other is for infectious reproductive pathogens such as IBR, BVDV, leptospirosis and vibriosis. 
Most vaccines against reproductive pathogens are labeled to be given prior to breeding. In some herds, however, management and labor constraints result in situations where preg-check time is the only chance to get the cows vaccinated. 
While it may be convenient, vaccinating for reproductive diseases during gestation is not exactly ideal. Most of the reproductive diseases we can vaccinate for can have substantial effects early (first two months or earlier) in gestation. Vaccinating a spring-calving cow herd in November means that 7-8 months might elapse between vaccination and the beginning of the next breeding season. This is long enough for the vaccine’s effects to have waned, as peak immunity probably occurs within a couple weeks of vaccination and then slowly declines. For this reason, gestational reproductive vaccine programs lack optimal timing.
It should be pointed out that there is little downside to using reproductive vaccines during pregnancy, if — and this is a big “if” — killed vaccines are used.  Vaccinating the herd during gestation with a killed reproductive vaccine will probably provide the herd a better level of protection than not vaccinating at all. 
In recent years, several vaccine manufacturers have promoted using modified live vaccines (MLV) in pregnant cow vaccination programs. It has long been known that administering modified live IBR vaccines to pregnant cows will result in abortions. This latest recommendation is therefore given with the caveat that animals must have been properly vaccinated pre-breeding that year with the same MLV vaccine. 
However, evidence is mounting that this practice is a bad idea.Stories of devastating abortion storms following pregnant cow MLV vaccination exist. These initially were noted to occur as a result of producers not following the label precautions regarding properly vaccinating cows with the same product before breeding the first year. But in recent years reports of abortion storms in cattle herds using MLV vaccines according to the label directions have surfaced (O’Toole, et al), making even label use of these vaccines suspect. 
Cattle producers know how difficult it is to maintain good reproductive rates in a cow herd when everything goes right. Given current information, it seems that the risk of using MLV vaccines in pregnant cows is not anywhere near the benefits that may be gained. Producers with questions about their vaccine program should consult with their veterinarian.
Source: Russ Daly

Saiba qual frango congelado levar pra casa

Saiba qual frango congelado levar pra casa
Veja quais marcas foram melhores avaliadas após os testes de procedimento e qualidade realizados pela PROTESTE.


Duas marcas apresentam esse problema, que pesa na balança e no seu bolso.

A presença do frango no cardápio da família é bastante recomendável, sendo uma importante fonte de proteínas para o organismo. E a boa notícia é que encontramos alguns produtos de muito boa qualidade e que não enganam no peso, como todos deveriam ser.
Na análise da higiene, verificamos se havia a presença de micro-organismos nocivos à saúde ou que indiquem mau estado de conservação ou deterioração, não encontramos problemas neste quesito. Analisamos também a presença de resíduos de medicamentos ou derivados. Felizmente, não encontramos resíduos de antibióticos e nitrofuranos nas amostras analisadas.

Procedimentos de fabricação
Na indústria de abate de aves, as etapas de resfriamento e a hidratação de carcaças e cortes são viabilizadas e aceleradas por meio de tanques com água resfriada. Esses procedimentos ocasionam um percentual de absorção de água em carcaças, que congelará junto com o produto caso não seja realizado um escorrimento adequado.  
O Ministério da Agricultura e Pecuária (Mapa) determina que, se a proporção da quantidade de água no peso da carcaça mais o peso dos miúdos na embalagem ultrapassarem o valor limite de 6%, o produto absorveu um excesso de água durante o pré-resfriamento por imersão.

Produtos com quantidades enganosas
Entre os frangos analisados, dois ultrapassaram esse teor máximo: Ad’oro e Rica, sendo que a primeira marca apresentou 7,6% de teor de água no descongelamento e, a segunda, absurdos 20,6%. Isso significa que, se você comprar um frango Rica de dois quilos, estará levando para casa, na verdade, apenas 1,6 quilo – o resto é água congelada. Assim, você pagará R$ 4,99 pelo quilo, quando, na verdade, deveria estar desembolsando R$ 3,96 – valor referente somente à carne. Dessa forma, esse produto pode se colocar no
mercado falsamente como um dos mais baratos, só que não faz parte, de fato, desse grupo. 
Como os dois produtos estão em desacordo com a legislação e causam danos econômicos para o consumidor, receberam avaliação “ruim” e tiveram sua nota limitada na avaliação final do teste. Cabe ressaltar que esta é a primeira vez que testamos o produto Ad’oro, mas o Rica já havia sido analisado em
2009 e o resultado foi muito semelhante. Na ocasião, notificamos o fabricante e as autoridades, mas nosso teste atual demonstra que nada foi feito para mudar a situação.

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Saiba qual frango congelado levar pra casa
Veja quais marcas foram melhores avaliadas após os testes de procedimento e qualidade realizados pela PROTESTE.
A carne de frango é uma importante fonte de proteínas e aminoácidos indispensáveis para a saúde. Para você preparar este alimento para a sua família, sem prejuízos após a compra, saiba quais marcas receberam o título de escolha certa e melhor do teste após os testes realizados pela PROTESTE.
O produto que recebeu a avaliação de melhor do teste foi o frango congelado Sadia, com melhor qualidade e menor teor de água. Nos supermercados o preço cobrado varia entre R$ 3,45 a R$ 6,75.
E o frango congelado indicado como a escolha certa foi o da marca Bonasa, com boa qualidade e preço mais em conta. O valor do produto varia entre R$ 3,39 a R$ 4,69.
Na hora da compra, uma dica: se você não encontrar nossa escolha certa em sua região, consulte na tabela ao lado
(www.proteste.org.br/alimentacao/nc/noticia/saiba-qual-frango-congelado-levar-pra-casa/download) as outras boas opções que estão disponíveis em sua cidade.

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